Projektnummer

0050850

Zusammenfassung

RNA interference (RNAi) describes the specific down-regulation of gene expression induced by homologous double-stranded RNAs, exploiting a naturally occurring pathway. To date, RNA interference can not be controlled once the RNAi triggers are delivered into cells. Moreover, the technique allows only for switching off the expression of a targeted gene. The possibility to switch on and off expression at particular times would widely broaden the scope of this method. In addition, it would be of great impact to turn on RNA interference when certain changes take place inside cells. Nuclid a...