Projektnummer

0051897

Zusammenfassung

Cutaneous leishmaniasis (CL) is a protozoan parasitic disease with 1-1.5 millions new cases per year worldwide and is widely regarded to be one of the most important opportunistic infections in HIV+ individuals. Recently, studies of CL in murine and other systems have identified several important mechanisms of host immune responses raised against Leishmania major. However, the relevance of these important findings for humans remains to be shown. The project aims at defining aspects of the immune response against L. major in CL patients and in patients co-infected with L. major and HIV,...