Projektdatenbank (ab 2004)

Projektnummer

0052539

Zusammenfassung

An emerging body of evidence suggests that many types of cancer contain a relatively rare subpopulation of cells that exhibit stem cell characteristics, and that this popultaion would represent the exclusive source for disease initiation and maintenance. However, the immediate mechanisms of stem cell-derived tumorigenesis remain mostly elusive. It is the long-term goal to combine the studies of tumor-initiating stem cells from a variety of human organs, e.g. the hematopoietic and neural systems, breast, prostate, or colon, to establish new therapeutic strategies targeting potentially c...