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Modification of host pathogen interaction in Mycobacterium ulcerans disease (BU) through heat treatment: basic mechanisms and clinical applications

Projektnummer

0052975

Zusammenfassung

In a 'proof of principle' study an innovative heat application system (phase change material [PCM]) to treat Mycobacterium ulcerans disease (Buruli ulcer [BU]) was successfully explored. It is easy to apply and to recharge in hot water, non-toxic, non-hazardous to the environment and cheap. This opens up a new era in the treatment of Mycobacterium ulcerans disease, in particular for communities with limited resources where the disease is most prevalent. Until today, treatment of BU is unsatisfactory with wide surgical excisions and skin grafting as the standard treatment over the past ...

Projektinformationen

Status:

Beendet

Startdatum:

01.05.2005

Enddatum:

30.04.2008

Fördersumme:

897.000 €

Profilbereich:

Beendete Förderinitiativen

Förderinitiative:

Wissen für morgen - Kooperative Forschungsvorhaben im sub-saharischen Afrika

Ausschreibung:

Tropical Medicine 2004