Projektnummer

0053596

Zusammenfassung

The "meningitis belt" of Sub-Saharan Africa records the highest incidence of meningococcal meningitis in the world. The disease occurs in epidemic cycles with devastating consequences. The mechanisms leading to the spread of clonal complexes of Neisseria meningitidis and to epidemics of disease are still unclear. In recent years, an increasing incidence of pneumococcal meningitis has been observed with a mortality significantly higher. The study focuses on systematic long-term analysis of the relationship between meningococcal colonization and disease in two districts in Ghana and in B...