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Simulation models for interactive cell motility - coupling intracellular dynamics and cell-cell adhesion (Extension)

Projektnummer

0054604

Zusammenfassung

Aim of this project is the description of the coordinated motion of cell aggregates in two dimensions. For this purpose, the single cell model of the previous project is combined with an already developed cell-based description of biological tissues. Similar to the previous treatment of cell-substrate adhesion proteins, the external cell-cell adhesion kinetics has to be coupled to the cell-internal actin dynamics. As a first step, this coupling is investigated by means of a section through an isolated cell pair in thin-film approximation. Next, the full treatment of the two-dimensional...

Projektinformationen

Status:

Beendet

Startdatum:

01.11.2010

Enddatum:

31.10.2012

Fördersumme:

139.000 €

Profilbereich:

Beendete Förderinitiativen

Förderinitiative:

Neue konzeptionelle Ansätze zur Modellierung und Simulation komplexer Systeme

Ausschreibung:

Biomoleküle-Zellen