Projektdatenbank (ab 2004)

Projektnummer

0056546

Zusammenfassung

Cancer epigenomes differ on more than 150,000 positions genome-wide in their methylation pattern from normal tissues. On one side these large differences provide the basis for the identification of candidate biomarkers, on the other side it poses the question how these alterations are initiated and what consequences they have on cancer surveillance. New high throughput sequencing technologies enable genomewide views on individual cancer genomes/epigenomes to a so far unmet extend. The concept of the professorship will be to further investigate the cancer genomes with a particular focus...