Projektnummer

0056754

Zusammenfassung

Eukaryotic cells are highly compartmentalized by membrane-engulfed organelles with distinct identities and specific duties. The endoplasmic reticulum (ER) and the Golgi apparatus (GA) are the most prominent hubs for protein sorting and posttranslational modifications. The intriguing regeneration ability of these organelles without a cellular mastermind suggests that physico-chemical self-organization plays a major role. So far, many protein families that support the biogenesis of ER and GA or mediate transport between them have been identified. However, self-organization principles tha...