Projektnummer

0060147

Zusammenfassung

As macroscopic systems, cells exhibit biochemical properties that are heavily influenced by the surrounding extracellular matrix. The project aims at rewiring living cells by in-situ lateral organization of membrane receptors and thus exert control over signaling networks by light. Wavelength-selective as well as two-photon photoactivatable supramolecular interaction pairs will be developed to direct receptor clustering with high spatiotemporal resolution. The one- and two-photon activation will facilitate a non-invasive protein organization in 2D and 3D. Combined with superresolution ...