Projektdatenbank (ab 2004)

Projektnummer

0060147

Zusammenfassung

As macroscopic systems, cells exhibit biochemical properties that are heavily influenced by the surrounding extracellular matrix. The project aims at rewiring living cells by in-situ lateral organization of membrane receptors and thus exert control over signaling networks by light. Wavelength-selective as well as two-photon photoactivatable supramolecular interaction pairs will be developed to direct receptor clustering with high spatiotemporal resolution. The one- and two-photon activation will facilitate a non-invasive protein organization in 2D and 3D. Combined with superresolution ...