Projektnummer

0061803

Zusammenfassung

Deciphering the physiological function of fundamental cellular processes has until recently been hindered by the lack of molecular tools to manipulate essential genes. Recent breakthroughs in the technology for genome engineering, such as CRISPR-Cas9, have allowed the characterization of these under-studied processes. In the frame of this project the research team proposes to use these new tools for the creation of a cell that will lose the ability of DNA replication during any point of the bacterial life cycle. With this approach the researchers intend to characterize the basic princi...