Projektdatenbank (ab 2004)

Projektnummer

0062720

Zusammenfassung

Life on Earth is proposed to have originated in hot environments, and later adapted to lower temperatures. The first organisms were potentially heat-loving microorganisms with temperature optima of at least 60°C or even more. Despite this assumption, mostly the adaptation of proteins and whole cells from cold or moderate to hot environments has been subject to numerous experimental and theoretical studies. In contrast, this project aims at looking to the more realistic scenario attempting to evolve a mesophilic microorganism from a thermophilic ancestor within a couple of hundred gener...