Projektnummer

0062907

Zusammenfassung

Eukaryotic cells often withstand incredible amounts of stress such as extreme temperatures, mechanical damage or exposure to toxins. In response, cells can form "stress granules" which are membrane-less organelles in the cytosol containing RNA, nucleoproteins (together called ribonucleoproteins or RNPs) and several enzymes as well as other proteins that sequester, protect and possibly repair damaged proteins having been unfold due to the applied stress. The role of RNA in such granules is largely viewed as passive. However, as the functions of RNA have been underestimated several times...