Projektnummer

0063738

Zusammenfassung

We now have technology to replace entire genomes with synthesized DNA. Synthetic living systems containing this designer DNA can be used as tools to investigate what is possible to achieve with life's molecular building blocks. The world's first fully synthetic eukaryotic organism, the yeast S. cerevisiae 2.0 (Sc2.0), was pre-programmed with the radical ability to rearrange its genome on demand in a process called SCRaMbLE. The project team will use SCRaMbLE to investigate three mysteries of living systems encoded in their DNA: (1) what is the minimal copy number of a core cellular function re...