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The spark of life: initiation of transcription in embryos, and recapitulating such in synthetic nuclei

Projektnummer

0063741

Zusammenfassung

When an egg is fertilized, it contains all the information that is needed to make an organism. For a brief period of time, the embryo relies on building blocks that it received from its mother but very soon thereafter, it starts to use the instructions that are encoded in its DNA to make its own building blocks. The research team terms this event 'the spark of life', because it is the moment when the embryo takes control over its own development. The team will determine the components that are involved in sparking life in the embryo, how these components assemble dynamically, and how t...

Projektinformationen

Status:

Beendet

Startdatum:

01.07.2018

Enddatum:

31.07.2024

Fördersumme:

3.268.590 €

Profilbereich:

Beendete Förderinitiativen

Förderinitiative:

Leben? - Ein neuer Blick der Naturwissenschaften auf die grundlegenden Prinzipien des Lebens