The importance of neutrophil-derived enzymes for the processing of auto-antigens and inflammatory mediators
Projektnummer
0066481
Zusammenfassung
The current project is aimed to clarify the role of NET-borne enzymes and proteins such as proteases, glycosidases and proteasomal subunits on the anti-inflammatory properties of NETs and their role in antigen presentation. The project partners will study in detail the presence and composition of functionally active proteasomes in neutrophils and associated with NETs. How other enzymes associated with NETs, such as PADI4, proteases and glycosidases are contributing to the anti-inflammatory properties of NETs will also be part of the current research project. Lastly, the consortium want...
Projektinformationen
Status:
Beendet
Startdatum:
01.01.2021
Enddatum:
31.12.2023
Fördersumme:
500.000 €
Profilbereich:
Gesellschaftliche Transformationen
Förderinitiative:
Trilaterale Partnerschaften - Kooperationsvorhaben zwischen Wis- senschaftler(inne)n aus der Ukraine, Russland und Deutschland