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The importance of neutrophil-derived enzymes for the processing of auto-antigens and inflammatory mediators

Projektnummer

0066481

Zusammenfassung

The current project is aimed to clarify the role of NET-borne enzymes and proteins such as proteases, glycosidases and proteasomal subunits on the anti-inflammatory properties of NETs and their role in antigen presentation. The project partners will study in detail the presence and composition of functionally active proteasomes in neutrophils and associated with NETs. How other enzymes associated with NETs, such as PADI4, proteases and glycosidases are contributing to the anti-inflammatory properties of NETs will also be part of the current research project. Lastly, the consortium want...

Projektinformationen

Status:

Beendet

Startdatum:

01.01.2021

Enddatum:

31.12.2023

Fördersumme:

500.000 €

Profilbereich:

Gesellschaftliche Transformationen

Förderinitiative:

Trilaterale Partnerschaften - Kooperationsvorhaben zwischen Wis- senschaftler(inne)n aus der Ukraine, Russland und Deutschland