Projektnummer

0066878

Zusammenfassung

The shape and function of tissues, organs, and organisms are profoundly linked and emerge during the process of morphogenesis. Traditionally, the underlying principles of morphogenesis have been investigated by studying the embryogenesis of optically and genetically accessible model species. However, due to the intrinsic complexity of the evolutionarily evolved molecular, cellular, and tissue feedbacks, inferring the rules of morphogenesis from watching and manipulating embryogenesis is a formidable challenge. Here, the research team proposes to develop an in vitro tissue reconstitutio...