Projektdatenbank (ab 2004)

Projektnummer

0066895

Zusammenfassung

A major driver for the emergence of complex life was the evolution of organelles, which disable cross-talk between cellular processes. In eukaryotes replication and transcription have been confined to the nucleus while the third central dogma process - translation - occurs in the cytoplasm. This step was accompanied by the biogenesis of a complex transport machinery that regulates all molecular traffic across the nuclear envelope. Analogously, the design of artificial organelles harboring complex functionality is challenging due to the necessity of a suitable membrane transport machine...