Projektdatenbank (ab 2004)

Projektnummer

0067704

Zusammenfassung

Numerous clinically relevant aspects of COVID-19 can be assessed neither in ordinary 2D cell culture nor in small animal experiments, constituting a main obstacle for drug development and therapy evaluation. This project will apply bioengineered human organ-on-chip platforms to recapitulate the complex interplay between host tissue and virus to understand the viral pathogenesis. The DiseaseX-Chip consortium will develop SARS2-infectable mini-chips using modern biomanufacturing technologies such as bioprinting and human multi-cellular 3D cultures resembling airways and blood vessels, to...