Projektnummer

0070223

Zusammenfassung

Reactivation of latent viral infection poses a significant threat to immunosuppressed patients in transplantation medicine. BK polyomavirus (BKPyV) is an underexplored virus responsible for nephropathy or hemorrhagic cystitis in a significant number of kidney or allogeneic hematopoietic stem cell transplant recipients. Currently, there is no vaccine, and drugs are urgently needed for preemptive treatment to prevent organ damage. This interdisciplinary project addresses the major challenges that have hindered drug development against BKPyV. The project team synergistically combines specific exp...