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Cas13d based antiviral platform to treat acute Bunyavirus infections

Projektnummer

0070256

Zusammenfassung

The current SARS-CoV-2 pandemic has dramatically demonstrated the urgent need of effective antivirals to treat infected patients to save lives. More than 700 RNA-viruses are available that have a similar pathogenic potential to induce the next pandemic or epidemic for which neither vaccines nor antivirals are available. Among those viruses with the greatest risk potential to threaten our health are Bunyaviruses represented by Rift Valley Fever Virus (RVFV) and the Lassa Fever Virus (LASV) according to WHO. To combat these potential treats, the project team adapted the prokaryotic CRISP...