Projektnummer

N000664

Zusammenfassung

Age-related diseases, such as Alzheimer's disease (AD), are becoming increasingly common in the society. The AD field is currently changing its approaches from studying the late-stage AD pathology to trying to understand early-stage pathophysiology. This has a greater potential for therapeutic intervention. One key element that is still unknown is the mechanism behind early disease progression, which causes the transition from faulty neuronal circuits to clinically-evident memory decline. The research group hypothesize that failures in neuronal components such as mitochondria and endop...