Projektdatenbank (ab 2004)

Projektnummer

N000685

Zusammenfassung

The brain consists of a vast network of nerve cells connected by synapses - cellular devices specialized for the transmission of information. According to a fundamental doctrine in neuroscience, changes to synapse strength, cued by experience or sensory input, represent a major mechanism by which nervous systems learn new tasks or store new memories. An implicit, yet often ignored corollary of this assertion is that strengths of synaptic connections should not change spontaneously, that is, in manners unrelated to functionally relevant cues. Recent studies suggest, however, that synaps...