Projektnummer

N000714

Zusammenfassung

An universal finding across species is that the formation of memories requires differential gene-expression in brain cells. The activation and inactivation of particular genes in response to specific stimuli is a tightly controlled process and its deregulation contributes to neurodegenerative and neuropsychiatric diseases. ?Epigenetic processes" play a key role in the orchestration of these gene-expression dynamics and have been linked to brain diseases. One key epigenetic processes is linked to alterations that regulate the 3D structure of DNA and thereby define if a particular region...