Projektdatenbank (ab 2004)

Projektnummer

N000718

Zusammenfassung

Salmonella enterica is a highly diverse food-borne and zoonotic bacterial pathogen causing a major health concern and economic burden worldwide. In recent years, the prevalence of multi-drug resistant S. enterica strains and invasive infections in humans has been rapidly increasing, challenging the traditional preventions and treatment protocols. The main pathogenicity hallmark of S. enterica is its ability to invade non-phagocytic host cells, a phenotype which is absolutely required to cause disease in humans and animals. Our goal is to identify and characterize non-toxic, non-antibio...