Peptide-based crystallographic fragment screening for fast and efficient discovery of lead structures against zoonotic viral diseases
Projektnummer
0069401
Zusammenfassung
The aim of this project is to advance novel strategies for efficient and fast development of compounds for fighting emerging (zoonotic) viral diseases. A key problem in drug development via fragment screening is that the organic chemistry necessary for fragment linking is relatively slow, labor-intensive and not easily accessible. In contrast, synthesis of peptides and many peptidomimetics can be conducted in a highly automated and parallel fashion. In this project, the researchers will establish technologies for fast and efficient development of potent inhibitors of two proteases as t...
Projektinformationen
Status:
Beendet
Startdatum:
01.03.2022
Enddatum:
31.12.2025
Fördersumme:
499.500 €
Profilbereich:
Exploration
Förderinitiative:
Innovative Ansätze in der antiviralen Wirkstoffentwicklung